生物
DNA甲基化
表观遗传学
转座因子
遗传学
RNA导向的DNA甲基化
甲基化
表观遗传学
体育锻炼的表观遗传学
基因
基因组
基因表达
作者
Robert A. Martienssen,Vincent Colot
出处
期刊:Science
[American Association for the Advancement of Science (AAAS)]
日期:2001-08-10
卷期号:293 (5532): 1070-1074
被引量:510
标识
DOI:10.1126/science.293.5532.1070
摘要
Plants and filamentous fungi share with mammals enzymes responsible for DNA methylation. In these organisms, DNA methylation is associated with gene silencing and transposon control. However, plants and fungi differ from mammals in the genomic distribution, sequence specificity, and heritability of methylation. We consider the role that transposons play in establishing methylation patterns and the epigenetic consequences of their perturbation.
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