转导(生物物理学)
生物传感器
纳米技术
材料科学
触觉传感器
微流控
触觉知觉
信号(编程语言)
仿生学
计算机科学
生物物理学
神经科学
感知
生物
人工智能
机器人
程序设计语言
作者
Ting Wang,Dianpeng Qi,Hui Yang,Zhiyuan Liu,Ming Wang,Wan Ru Leow,Geng Chen,Jiancan Yu,Ke He,Hongwei Cheng,Yun‐Long Wu,Han Zhang,Xiaodong Chen
标识
DOI:10.1002/adma.201803883
摘要
Tactile sensors capable of perceiving biophysical signals such as force, pressure, or strain have attracted extensive interest for versatile applications in electronic skin, noninvasive healthcare, and biomimetic prostheses. Despite these great achievements, they are still incapable of detecting bio/chemical signals that provide even more meaningful and precise health information due to the lack of efficient transduction principles. Herein, a tactile chemomechanical transduction strategy that enables the tactile sensor to perceive bio/chemical signals is proposed. In this methodology, pyramidal tactile sensors are linked with biomarker-induced gas-producing reactions, which transduce biomarker signals to electrical signals in real time. The method is advantageous as it enhances electrical signals by more than tenfold based on a triple-step signal amplification strategy, as compared to traditional electrical biosensors. It also constitutes a portable and general platform capable of quantifying a wide spectrum of targets including carcinoembryonic antigen, interferon-γ, and adenosine. Such tactile chemomechanical transduction would greatly broaden the application of tactile sensors toward bio/chemical signals perception which can be used in ultrasensitive portable biosensors and chemical-responsive chemomechanical systems.
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