神经科学
帕金森病
疾病
医学
功能磁共振成像
心理学
神经影像学
病理
作者
Massimo Filippi,Elisabetta Sarasso,Noemi Piramide,Federica Agosta
标识
DOI:10.1016/bs.irn.2018.08.005
摘要
Functional MRI (fMRI) has been widely used to study abnormal patterns of brain connectivity at rest and activation during a variety of tasks in patients with idiopathic Parkinson's disease (PD). fMRI studies in PD have led to a better understanding of many aspects of the disease including both motor and non-motor symptoms. Although its translation into clinical practice is still at an early stage, fMRI measures hold promise for multiple clinical applications in PD, including the early detection, predicting future change in clinical status, and as a marker of alterations in brain physiology related to neurotherapeutic agents and neurorehabilitative strategies.
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