Serological Evidence of Human Infection with Congo-Crimean Hemorrhagic Fever Virus in Greece *

Sixty-five residents in a rural area of northern Greece were tested for circulating antibodies against Congo-Crimean hemorrhagic fever virus; antibodies were demonstrated in four by immunofluorescence and hemagglutination-inhibition tests. While the virus had been previously isolated in the area, this is the first time that evidence of human infection in nature has been observed in Greece.