Synthesis of N-(2 amino benzothiazole) methacylamide monomer and its copolymers for antimicrobial coating application by RAFT polymerization

Monomer with thiazole moiety was synthesized and copolymerized with butyl acrylate and methyl methacrylate by reversible addition fragmentation chain transfer emulsion polymerization. The chain transfer agent was synthesized using N-ethyl piperazine, carbon disulfide, and ethyl 2-bromoisobutyrate. The wt% of monomer was varied from 3, 5, 7, 9, and 12 respectively. A antimicrobial activities of monomer and its copolymers were screened against E. coli, B. subtilis, C. albicans, and Aspergillus niger microorganisms. The synthesized monomer and chain transfer agent were characterized by 1H NMR, FTIR, and mass spectral analysis, whereas emulsion copolymers were characterized for their molecular weight, particle size, and FTIR analysis.