肺
核医学
医学
医学物理学
放射科
计算机科学
内科学
作者
Kent G. Benner,Justin Roper,Aparna H. Kesarwala,Seth Fehrs,Eduard Schreibmann,Kirk Luca
标识
DOI:10.1016/j.meddos.2024.08.003
摘要
This study investigated optimization settings that steepen the dose gradient as a function of target size for lung stereotactic body radiation therapy (SBRT). Sixty-eight lung SBRT patients with planning target volumes (PTVs) ranging from 2-203 cc were categorized into small (<20 cc), medium (20-50 cc), and large (>50 cc) groups. VMAT plans were generated using the normal tissue objective (NTO) to penalize the dose gradient at progressively steeper NTO fall-off values (0.1, 0.2, 0.3, 0.4, 0.5 mm
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