杜皮鲁玛
医学
特应性皮炎
不利影响
生活质量(医疗保健)
疾病
嗜酸性粒细胞
重症监护医学
皮肤病科
免疫学
内科学
哮喘
护理部
作者
Alex E Wright,W. C. Wood,Aakash Goyal
标识
DOI:10.1097/mop.0000000000001390
摘要
Purpose of review Dupilumab is an emerging medication that has shown efficacy for multiple atopic conditions. This review provides insight into the common conditions that are treated, mechanism of action, and continued innovation with the medication. Recent findings There continues to be applicability of dupilumab in treating a growing number of atopic conditions. Increasingly younger patient populations with eosinophil based conditions are being approved for this therapy. It is also considered as an additional option treatment for patients who cannot tolerate oral therapy or have adverse effects from other agents. Patients with more severe conditions are finally finding symptom stability while also being able to reduce reliance on corticosteroids. Patients as young as 6 months of age have benefited from treatment. Summary As atopic conditions become more prevalent, dupilumab has been shown to be successful in inducing remission of symptoms. Overall, it continues to be a promising treatment for reducing the burden of disease severity as well as improving the quality of life of affected children.
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