内分泌学
萎缩
糖尿病
人参皂甙
肌肉萎缩
骨骼肌
化学
医学
内科学
人参
病理
替代医学
作者
Man‐Ying Wang,Changjiu Cai,Wenqi Jin,Yunyun Zhao,Yue Mu,Ren Li-mei,Daqing Zhao,Fangbing Liu,Sun Liwei
出处
期刊:Phytomedicine
[Elsevier]
日期:2024-08-15
卷期号:134: 155964-155964
标识
DOI:10.1016/j.phymed.2024.155964
摘要
High glucose levels are a primary cause of diabetes-associated cellular dysfunction and tissue damage. Muscles are the key insulin target organ and therefore, have a high level of sensitivity to hyperglycemia. Our previous study revealed that 20(S)-ginsenoside Rg3 (S-Rg3) is a monomer with a good myogenic differentiation effect in ginsenoside. Furthermore, it can alleviate dexamethasone-induced muscle atrophy by protecting mitochondrial function. However, whether S-Rg3 is effective for diabetic-induced muscle atrophy has not been reported.
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