Mechanotransduction blocking: A march to scarless wound healing

In a recent work published in Science Translational Medicine by a Stanford team, Chen et al. uncover a comprehensive characterization of fibrosis in a large clinically relevant animal model, bringing in a new scarless wound healing concept of pharmacological blockade of mechanotransduction. The state-of-the-art strategy provides potential solutions to improve scar formation and tissue regeneration in the near future. In a recent work published in Science Translational Medicine by a Stanford team, Chen et al. uncover a comprehensive characterization of fibrosis in a large clinically relevant animal model, bringing in a new scarless wound healing concept of pharmacological blockade of mechanotransduction. The state-of-the-art strategy provides potential solutions to improve scar formation and tissue regeneration in the near future.