已入深夜,您辛苦了!由于当前在线用户较少,发布求助请尽量完整地填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!祝你早点完成任务,早点休息,好梦!

Relationship between Diabetes Status and Sarcopenia in Community-Dwelling Older Adults

肌萎缩 医学 糖尿病 内科学 老年学 内分泌学
作者
Kazuhei Nishimoto,Takehiko Doi,Kota Tsutsumimoto,Sho Nakakubo,Satoshi Kurita,Yuto Kiuchi,Hiroyuki Shimada
出处
期刊:Journal of the American Medical Directors Association [Elsevier BV]
卷期号:23 (10): 1718.e7-1718.e12 被引量:7
标识
DOI:10.1016/j.jamda.2022.07.020
摘要

Objectives Diabetes mellitus (DM) is associated with risk of sarcopenia. However, whether glycated hemoglobin (HbA1c) levels are associated with sarcopenia has not reached a consensus. The purpose of this study was to examine the association between diabetes status based on HbA1c levels and sarcopenia indices in community-dwelling older adults stratified by body mass index (BMI) status. Design An observational cross-sectional study. Setting and Participants General community setting. The participants were 18,940 community-dwelling older adults (mean age 73.7 ± 5.7 years, 45.0% men). Methods According to their medical history for diabetes mellitus and blood HbA1c levels the participants were classified into the control group (no DM history and HbA1c ≤5.6%), pre-DM group (no DM history and HbA1c 5.7%–6.4%), or DM group (DM history or HbA1c ≥6.5%). For assessments of sarcopenia, muscle mass and muscle strength were measured based on the clinical definition. Results A multiple logistic regression analysis showed that the DM group did not have a clear association with sarcopenia [odds ratio (OR) 1.06, 95% confidence interval (CI) 0.82–1.38] or low muscle mass (OR 1.15, 95% CI 0.94–1.39), and was associated with low muscle strength (OR 1.21, 95% CI 1.08–1.36) in the adjusted model including BMI. There was a positive correlation between BMI and skeletal muscle index (r = 0.57, P < .001). Stratified by BMI, the DM group was associated with low muscle mass among the underweight participants (OR 1.87, 95% CI 1.03–3.39), and low muscle strength among the overweight participants (OR 1.22, 95% CI 1.04–1.43). Conclusions and Implications Diabetes status was associated with low muscle mass and low muscle strength, and the association depended on BMI. Our findings could be helpful for identifying older adults with a high risk of sarcopenia, although further study is needed.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
coolkid应助科研通管家采纳,获得10
刚刚
1秒前
乐乐应助科研通管家采纳,获得10
1秒前
1秒前
Owen应助科研通管家采纳,获得10
1秒前
1秒前
深情安青应助科研通管家采纳,获得10
1秒前
充电宝应助科研通管家采纳,获得10
1秒前
充电宝应助科研通管家采纳,获得10
1秒前
cf2v发布了新的文献求助10
3秒前
积极的香菇完成签到 ,获得积分10
3秒前
7秒前
所所应助bulinggu采纳,获得10
7秒前
9秒前
sky完成签到,获得积分10
10秒前
12秒前
niuma发布了新的文献求助20
15秒前
bulinggu完成签到,获得积分10
16秒前
fancy完成签到 ,获得积分10
16秒前
爱宝乐宝福宝应助猫瓜西采纳,获得10
16秒前
16秒前
Jiangzhibing发布了新的文献求助10
16秒前
重要的小刘完成签到,获得积分10
17秒前
出租耳朵发布了新的文献求助10
17秒前
bulinggu发布了新的文献求助10
19秒前
20秒前
21秒前
碎碎念s完成签到,获得积分10
21秒前
小鱼完成签到 ,获得积分10
22秒前
23秒前
24秒前
S.S.N发布了新的文献求助10
24秒前
大大大大管子完成签到 ,获得积分10
24秒前
loong发布了新的文献求助10
24秒前
lina发布了新的文献求助10
27秒前
27秒前
28秒前
FashionBoy应助loong采纳,获得10
29秒前
Ding发布了新的文献求助10
31秒前
鬲木完成签到,获得积分20
31秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
‘Unruly’ Children: Historical Fieldnotes and Learning Morality in a Taiwan Village (New Departures in Anthropology) 400
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3989832
求助须知:如何正确求助?哪些是违规求助? 3531967
关于积分的说明 11255613
捐赠科研通 3270725
什么是DOI,文献DOI怎么找? 1805035
邀请新用户注册赠送积分活动 882181
科研通“疑难数据库(出版商)”最低求助积分说明 809208