CT Radiomics in Oncology: Insights into the Tumor Microenvironment of Hepatocellular Carcinoma

HomeRadiologyVol. 307, No. 1 PreviousNext Reviews and CommentaryEditorialCT Radiomics in Oncology: Insights into the Tumor Microenvironment of Hepatocellular CarcinomaJeong Hee Yoon , Haeryoung KimJeong Hee Yoon , Haeryoung KimAuthor AffiliationsFrom the Departments of Radiology (J.H.Y.) and Pathology (H.K.), Seoul National University Hospital, 101 Daehak-ro, Jongro-Gu, Seoul 03080, South Korea; and Departments of Radiology (J.H.Y.) and Pathology (H.K.), Seoul National University College of Medicine, Seoul, South Korea.Address correspondence to J.H.Y. (email: [email protected]).Jeong Hee Yoon Haeryoung KimPublished Online:Dec 13 2022https://doi.org/10.1148/radiol.222988MoreSectionsFull textPDF ToolsImage ViewerAdd to favoritesCiteTrack CitationsPermissionsReprints ShareShare onFacebookTwitterLinked In References1. Feng Z, Li H, Zhao H, et al. Preoperative CT for Characterization of Aggressive Macrotrabecular-Massive Subtype and Vessels That Encapsulate Tumor Clusters Pattern in Hepatocellular Carcinoma. Radiology 2021;300(1):219–229. Link, Google Scholar2. Yoon JH, Kim H. CT Characterization of Aggressive Macrotrabecular-Massive Hepatocellular Carcinoma: A Step Forward to Personalized Medicine. Radiology 2021;300(1):230–232. Link, Google Scholar3. Lewis S, Hectors S, Taouli B. Radiomics of hepatocellular carcinoma. Abdom Radiol (NY) 2021;46(1):111–123. Crossref, Medline, Google Scholar4. Feng Z, Li H, Liu Q, et al. CT Radiomics to Predict Macrotrabecular-Massive Subtype and Immune Status in Hepatocellular Carcinoma. Radiology 2023;307(1):e221291. Google Scholar5. Tomaszewski MR, Gillies RJ. The Biological Meaning of Radiomic Features. Radiology 2021;298(3):505–516. Link, Google Scholar6. Zou J, Luo C, Xin H, et al. The role of tumor-infiltrating B cells in the tumor microenvironment of hepatocellular carcinoma and its prognostic value: a bioinformatics analysis. J Gastrointest Oncol 2022;13(4):1959–1966. Crossref, Medline, Google Scholar7. Shen YC, Hsu CL, Jeng YM, et al. Reliability of a single-region sample to evaluate tumor immune microenvironment in hepatocellular carcinoma. J Hepatol 2020;72(3):489–497. Crossref, Medline, Google Scholar8. Dong LQ, Peng LH, Ma LJ, et al. Heterogeneous immunogenomic features and distinct escape mechanisms in multifocal hepatocellular carcinoma. J Hepatol 2020;72(5):896–908. Crossref, Medline, Google Scholar9. Wang JH, Li XS, Tang HS, et al. Vessels that encapsulate tumor clusters (VETC) pattern predicts the efficacy of adjuvant TACE in hepatocellular carcinoma. J Cancer Res Clin Oncol 2022. https://doi.org/10.1007/s00432-022-04323-4. Published online September 1, 2022. Crossref, Google Scholar10. Fang JH, Xu L, Shang LR, et al. Vessels That Encapsulate Tumor Clusters (VETC) Pattern Is a Predictor of Sorafenib Benefit in Patients with Hepatocellular Carcinoma. Hepatology 2019;70(3):824–839. Crossref, Medline, Google ScholarArticle HistoryReceived: Nov 19 2022Revision requested: Nov 22 2022Revision received: Nov 25 2022Accepted: Nov 28 2022Published online: Dec 13 2022 FiguresReferencesRelatedDetailsAccompanying This ArticleCT Radiomics to Predict Macrotrabecular-Massive Subtype and Immune Status in Hepatocellular CarcinomaDec 13 2022RadiologyRecommended Articles TACE Treatment in Patients with Sorafenib-treated Unresectable Hepatocellular Carcinoma in Clinical Practice: Final Analysis of GIDEONRadiology2016Volume: 279Issue: 2pp. 630-640Correlation of Doxorubicin Delivery and Tumor Necrosis after Drug-eluting Bead Transarterial Chemoembolization of Rabbit VX2 Liver TumorsRadiology2016Volume: 280Issue: 3pp. 752-761CT Characterization of Aggressive Macrotrabecular-Massive Hepatocellular Carcinoma: A Step Forward to Personalized MedicineRadiology2021Volume: 300Issue: 1pp. 230-232CT Radiomics to Predict Macrotrabecular-Massive Subtype and Immune Status in Hepatocellular CarcinomaRadiology2022Volume: 307Issue: 1Advanced Hepatocellular Carcinoma: Pretreatment Contrast-enhanced CT Texture Parameters as Predictive Biomarkers of Survival in Patients Treated with SorafenibRadiology2018Volume: 288Issue: 2pp. 445-455See More RSNA Education Exhibits Combining Radioembolization And Immune Checkpoint Inhibitors For The Treatment Of Hepatocellular Carcinoma: Mutually Beneficial Therapies For A Challenging DiseaseDigital Posters2021Common Patterns of Change in ADC Histogram of Hepatocellular Carcinoma Lesions Following Transarterial Chemoembolization and Their Relationship with Patients’ PrognosisDigital Posters2019Seeing the Forest for the Trees: The New Systemic Options to Treat Hepatocellular CarcinomaDigital Posters2019 RSNA Case Collection LI-RADS 5RSNA Case Collection2022Hepatic AngiosarcomaRSNA Case Collection2021Radioembolization of Liver Metastasis RSNA Case Collection2020 Vol. 307, No. 1 Metrics Altmetric Score PDF download