Occurrence and stability of PCMX in water environments and its removal by municipal wastewater treatment processes

Para-chloro-meta-xylenol (PCMX) is a synthetic antiseptic used extensively to control the spread of germs and viruses, and as a result, enormous amount of PCMX could be discharged to water environments through drainage. To investigate the extent of PCMX contamination, water samples were collected from rivers and coastal waters in Hong Kong, and PCMX concentrations were determined by a newly developed method using liquid chromatography-tandem mass spectrometry combined with stable isotope-dilution. We discovered widespread PCMX pollution in the water environment. Then, we revealed for the first time that PCMX in wastewater is not effectively removed by chemically enhanced primary treatment (CEPT), one of the wastewater treatment processes used in Hong Kong (∼75% of wastewater) and other megacities around the world. This suggests that the CEPT effluent or the primary treatment effluent is an unintended continuous source of pollution for PCMX in water environments. Finally, we found that PCMX was relatively stable in the water environment and could pose a risk to aquatic organisms. These findings underscore the importance of raising public awareness of the environmental consequences from overuse of PCMX-based disinfectants and the need to reevaluate the various wastewater treatment processes in removing PCMX.