广告
寡核苷酸
肽
计算生物学
药理学
药品
化学
医学
生物化学
生物
DNA
作者
Jesper Christensen,Inga Bjørnsdottir,Anders Sonesson,Steve R. Hood
出处
期刊:Xenobiotica
[Informa]
日期:2023-04-03
卷期号:53 (4): 332-337
标识
DOI:10.1080/00498254.2023.2223666
摘要
Challenges within peptide and oligonucleotide ADME (absorption, distribution, metabolism and elimination) and scientific ideas on how to solve them were presented and discussed at the DMDG (Drug Metabolism and Discussion Group) Peptide and Oligonucleotide ADME Workshop 2022 (2nd and 3rd of October 2022). This meeting report summarises the presentations and discussions from this workshop.The following topics were covered:Overview of the drug modality landscapeMetabolism & modellingAnalytical challengesDrug-drug interactions reports from industry working groupsRegulatory interactions
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