Management Strategy for Gallbladder Polypoid Lesions: Results of a 5-Year Single-Center Cohort Study

医学 胆囊 胃肠病学 内科学 子宫腺肌瘤病 息肉切除术 胆囊切除术 腺癌 单中心 单变量分析 前瞻性队列研究 病态的 多元分析 癌症 结肠镜检查 结直肠癌
作者
Feng Tian,Yuxin Ma,Lei Zhu,Wei Liu,Tao Hong,Xiaodong He,Qiang Qu
出处
期刊:Digestive Surgery [Karger Publishers]
卷期号:39 (5-6): 263-273 被引量:5
标识
DOI:10.1159/000529221
摘要

Controversy remains about the classification, differential diagnosis, and treatment strategy for gallbladder polypoid lesions (GPLs). This study sought to explore the individualized treatment strategy for GPLs.We retrospectively studied 642 consecutive patients with GPLs from January 2015 to May 2020. Univariate and multivariable analyses were performed to explore the potential risk factors for neoplastic polyps. The outcome of laparoscopic gallbladder-preserving polypectomy (GPP) was evaluated and compared with that of laparoscopic cholecystectomy (LC).Of 642 enrolled patients, 572 underwent LC, and 70 underwent GPP. Pathologically, the majority of GPLs were cholesterol polyps (68.4%), followed by adenomyomatosis (19.9%), benign adenoma (7.3%), adenocarcinoma (3.6%), and rare pathological types (0.8%). Additionally, 66.3% (379/572) of the LC cases were classified as non-neoplastic, and 33.7% (193/572) neoplastic polyps. Multivariate analysis demonstrated that single polyps (OR 1.956, 95% CI: 1.121-3.412; p = 0.018), polyps located at the gallbladder fundus (OR 4.326, 95% CI: 2.179-8.591; p < 0.001), polyps not less than 14 mm (OR 2.833, 95% CI: 1.614-4.973; p < 0.001), and polyps with a broad base (OR 4.173, 95% CI: 1.743-9.990; p = 0.001) were independent risk factors for neoplastic polyps. The 5-year prospective results after GPP showed that the 1-year and 3-year polyp recurrence rates were 13.2% and 23.4%, respectively.The majority of GPLs are cholesterol or other benign lesions without malignant potential. LC is the main treatment procedure for GPLs with a high neoplastic risk. GPP is potentially feasible and could be an alternative management strategy for a group of GPLs patients who meet the selection criteria.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
淡然以柳完成签到 ,获得积分10
刚刚
dolabmu完成签到 ,获得积分10
3秒前
崔崔完成签到 ,获得积分10
7秒前
SYLH应助xcxc采纳,获得10
8秒前
wp4455777完成签到,获得积分10
9秒前
十一完成签到,获得积分10
9秒前
ru完成签到 ,获得积分10
11秒前
慧木完成签到 ,获得积分10
11秒前
WW完成签到 ,获得积分10
12秒前
小高同学完成签到,获得积分10
13秒前
轻轻1完成签到,获得积分10
16秒前
17秒前
大橙子发布了新的文献求助10
21秒前
iuhgnor完成签到,获得积分10
24秒前
可夫司机完成签到 ,获得积分10
27秒前
yang完成签到,获得积分10
29秒前
一1完成签到 ,获得积分10
31秒前
jiaolulu完成签到,获得积分10
31秒前
量子星尘发布了新的文献求助10
33秒前
爆米花应助LiZhao采纳,获得10
33秒前
轻轻完成签到,获得积分10
36秒前
Orange应助jiaolulu采纳,获得10
36秒前
xcxc完成签到,获得积分10
38秒前
water应助科研通管家采纳,获得50
38秒前
38秒前
默存完成签到,获得积分10
41秒前
风中的金鱼完成签到 ,获得积分10
43秒前
橙汁完成签到,获得积分10
44秒前
普鲁卡因发布了新的文献求助10
47秒前
cora完成签到 ,获得积分10
53秒前
徐伟康完成签到 ,获得积分10
53秒前
Minicoper完成签到,获得积分10
1分钟前
科研通AI5应助普鲁卡因采纳,获得10
1分钟前
111完成签到 ,获得积分10
1分钟前
奥特曼完成签到 ,获得积分10
1分钟前
苏苏完成签到,获得积分10
1分钟前
大橙子完成签到,获得积分10
1分钟前
kelite完成签到 ,获得积分10
1分钟前
火星上的雨柏完成签到 ,获得积分10
1分钟前
JY完成签到,获得积分10
1分钟前
高分求助中
【提示信息,请勿应助】关于scihub 10000
Les Mantodea de Guyane: Insecta, Polyneoptera [The Mantids of French Guiana] 3000
徐淮辽南地区新元古代叠层石及生物地层 3000
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
Handbook of Industrial Diamonds.Vol2 1100
Global Eyelash Assessment scale (GEA) 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 550
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 4038128
求助须知:如何正确求助?哪些是违规求助? 3575831
关于积分的说明 11373827
捐赠科研通 3305610
什么是DOI,文献DOI怎么找? 1819255
邀请新用户注册赠送积分活动 892655
科研通“疑难数据库(出版商)”最低求助积分说明 815022