丁型肝炎病毒
病毒学
乙型肝炎病毒
丁型肝炎
流行病学
医学
乙型肝炎
基因型
病毒
生物
乙型肝炎表面抗原
内科学
基因
生物化学
出处
期刊:PubMed
日期:2022-10-20
卷期号:30 (10): 1017-1021
被引量:1
标识
DOI:10.3760/cma.j.cn501113-20221019-00498
摘要
Hepatitis D virus (HDV) is a defective RNA virus with 8 genotypes, which requires hepatitis B virus (HBV) for its replication both in co-infection (HDV infection occurs when people become infected with both hepatitis B and D simultaneously) and super-infection (HDV infection after infected with hepatitis B). Due to persistency of anti-HDV in the superinfected patient, the most epidemiology data of HDV infection suggests HBV/HDV super-infection. Because of inadequate awareness and effective HBV vaccination programme, HDV infection screen was not specific recommended, except for risk population recommended by AASLD. However, the disease burden of HDV infection was not fully understood and might be underestimated. This review summarized the anti-HDV and HDV genotype epidemiology and the screening of HDV infection.丁型肝炎病毒(HDV)是一种缺陷RNA病毒,它需要借助乙型肝炎病毒(HBV)以完成其生命周期。慢性HDV感染是最严重的病毒性肝炎形式,与单纯HBV感染相比,HDV/HBV重叠感染会加速疾病的进展。然而,HDV感染的疾病负担一直未得到充分认识,有可能是被低估的。近年来,有关丁型肝炎的研究逐步增多,现对抗-HDV流行病学及筛查进展进行综述。.
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