生物
局部适应
进化生物学
适应(眼睛)
多效性
自然选择
固定(群体遗传学)
选择性扫描
基因
选择(遗传算法)
人口
遗传学
基因复制
等位基因
表型
神经科学
人口学
人工智能
社会学
计算机科学
单倍型
作者
Gabriele Nocchi,James R. Whiting,Sam Yeaman
标识
DOI:10.1073/pnas.2406832121
摘要
Global adaptation occurs when all populations of a species undergo selection toward a common optimum. This can occur by a hard selective sweep with the emergence of a new globally advantageous allele that spreads throughout a species’ natural range until reaching fixation. This evolutionary process leaves a temporary trace in the region affected, which is detectable using population genomic methods. While selective sweeps have been identified in many species, there have been few comparative and systematic studies of the genes involved in global adaptation. Building upon recent findings showing repeated genetic basis of local adaptation across independent populations and species, we asked whether certain genes play a more significant role in driving global adaptation across plant species. To address this question, we scanned the genomes of 17 plant species to identify signals of repeated global selective sweeps. Despite the substantial evolutionary distance between the species analyzed, we identified several gene families with strong evidence of repeated positive selection. These gene families tend to be enriched for reduced pleiotropy, consistent with predictions from Fisher’s evolutionary model and the cost of complexity hypothesis. We also found that genes with repeated sweeps exhibit elevated levels of gene duplication. Our findings contrast with recent observations of increased pleiotropy in genes driving local adaptation, consistent with predictions based on the theory of migration-selection balance.
科研通智能强力驱动
Strongly Powered by AbleSci AI