Magnetization-transfer flow-independent dark-blood delayed enhancement cardiac MRI optimizes discrimination of ST-elevation myocardial infarct borders

医学 核医学 心肌梗塞 磁共振成像 血流 置信区间 图像质量 心脏病学 一致性 神经组阅片室 内科学 放射科 神经学 图像(数学) 精神科 人工智能 计算机科学
作者
Paulina Poskaite,Christian Kremser,Mathias Pamminger,Felix Troger,Gert Reiter,Sebastian J. Reinstadler,Bernhard Metzler,Wolfgang G Rehwald,Raymond J. Kim,Agnes Mayr
出处
期刊:European Radiology [Springer Science+Business Media]
标识
DOI:10.1007/s00330-024-11192-7
摘要

Abstract Objectives To prospectively compare image quality and infarct sizing methods between magnetization-transfer “flow-independent dark-blood delayed enhancement” (MT-FIDDLE) and standard “bright-blood”-late gadolinium enhancement (LGE) cardiac-magnetic-resonance (CMR) sequence. Methods “Bright-blood”-LGE and MT-FIDDLE sequence were acquired in 110 patients at 4 days ( n = 33), 4 months ( n = 39) and 12 months ( n = 38) after acute ST-elevation myocardial infarction (STEMI). Subjective image quality, including confidence in infarct segmentation and blood-pool bordering, were each rated on a 4-point Likert scale. Objective image quality was assessed by the detectability index (DI). Infarct volumes derived via full-width at half-maximum (FWHM) and different number of standard deviations (“n-SD”) methods on MT-FIDDLE images were compared with FWHM and reference 5-SD results from “bright-blood-LGE images. Results Overall subjective median image quality was excellent for both LGE sequences. Qualitative analysis revealed a significantly higher confidence in infarct segmentation and in blood-pool bordering for MT-FIDDLE as compared to “bright-blood”-LGE (all p < 0.001). Infarct volumes assessed by the FWHM technique on MT-FIDDLE and “bright-blood”-LGE showed excellent agreement overall (Concordance correlation coefficient, CCC = 0.96). The 3-SD technique for MT-FIDDLE showed the best agreement with the 5-SD method for “bright-blood”-LGE overall (CCC = 0.94), as well as in the subgroup with excellent confidence in infarct segmentation on “bright-blood”-LGE (CCC = 0.96). DI of scar versus LV blood-pool was higher for MT-FIDDLE (8.9 ± 5.5) compared to “bright-blood”-LGE sequence (2.0 ± 1.5; p < 0.001). Conclusion MT-FIDDLE significantly optimizes the discrimination between myocardial infarction and adjacent blood-pool in STEMI patients. As compared to the established 5-SD technique on “bright-blood”-LGE, the 3-SD method on MT-FIDDLE results in consistent infarct volumes. Key Points Question Does magnetization-transfer “flow-independent dark-blood delayed enhancement” (MT-FIDDLE) offer any benefits over standard “bright-blood”-late gadolinium enhancement (LGE) cardiac-magnetic-resonance (CMR) for identifying STEMI infarct borders? Findings MT-FIDDLE image quality was higher than LGE CMR and measured infarct volume comparability to the standard 5-SD-threshold-technique. Clinical relevance MT-FIDDLE facilitates the assessment of myocardial infarctions at the subendocardial border, improving the discrimination between myocardial infarction and adjacent blood-pool in STEMI patients.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
1秒前
顺顺利利完成签到,获得积分10
1秒前
1秒前
1秒前
1秒前
海人完成签到 ,获得积分10
2秒前
fireking_sid完成签到,获得积分10
2秒前
科研通AI5应助hhh采纳,获得10
3秒前
11发布了新的文献求助10
3秒前
4秒前
俗丨发布了新的文献求助10
4秒前
Murphy完成签到 ,获得积分10
5秒前
大胆胡萝卜完成签到,获得积分10
5秒前
细腻的歌曲完成签到,获得积分10
6秒前
6秒前
aam完成签到,获得积分10
6秒前
超级无敌奥特大王完成签到,获得积分10
6秒前
XJY完成签到,获得积分10
6秒前
猪猪侠有腹肌了完成签到,获得积分20
7秒前
Sw完成签到,获得积分10
7秒前
思源应助爱撒娇的紫菜采纳,获得10
7秒前
7秒前
Jessica完成签到 ,获得积分10
8秒前
Amy发布了新的文献求助10
8秒前
可靠橘子完成签到,获得积分10
8秒前
光崽是谁完成签到,获得积分10
9秒前
吴雪完成签到 ,获得积分10
9秒前
张兰发布了新的文献求助10
9秒前
单纯的易文完成签到 ,获得积分10
9秒前
刘宇完成签到,获得积分10
10秒前
10秒前
honting完成签到,获得积分10
10秒前
唐落音完成签到,获得积分10
11秒前
11完成签到,获得积分10
11秒前
超世完成签到,获得积分10
11秒前
whandzxl完成签到,获得积分10
11秒前
乐乐应助whatever采纳,获得30
12秒前
细腻海蓝完成签到,获得积分10
13秒前
doctoranran完成签到,获得积分10
13秒前
慕青应助苹果初阳采纳,获得10
14秒前
高分求助中
Nickel, Cobalt and Palladium Catalysed Infarction with Ventricular following rich structural diversity 1000
A new approach to the extrapolation of accelerated life test data 1000
Cognitive Neuroscience: The Biology of the Mind 1000
Technical Brochure TB 814: LPIT applications in HV gas insulated switchgear 1000
Immigrant Incorporation in East Asian Democracies 600
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3968608
求助须知:如何正确求助?哪些是违规求助? 3513486
关于积分的说明 11168243
捐赠科研通 3248926
什么是DOI,文献DOI怎么找? 1794540
邀请新用户注册赠送积分活动 875188
科研通“疑难数据库(出版商)”最低求助积分说明 804676