Nanomedicine enhanced photodynamic therapy for triple negative breast cancer

In this study, we synthesized and prepared nanomedicines with microenvironment responsive and optical activity targeting the high ROS, hypoxic, and acidic characteristics of the tumor microenvironment. We speculate that using MOC-68 mediated photodynamic therapy to inhibit tumor growth, combined with hydrogen sulfide loaded donor DATS, and integrating hollow mesoporous MnO2 nanoparticles to improve PDT efficiency, while achieving MRI visualization monitoring of the treatment process. We conducted some preliminary experiments, and the research results preliminarily confirmed that the hypothesis of the topic is reasonable and has potential.