Clinical and safety outcomes of acute stenting plus thrombectomy for carotid tandem lesions with large ischemic core

医学 改良兰金量表 颈动脉支架置入术 优势比 脑出血 冲程(发动机) 置信区间 外科 病变 回顾性队列研究 内科学 缺血性中风 格拉斯哥昏迷指数 颈动脉内膜切除术 颈动脉 缺血 工程类 机械工程
作者
Yakub Deliktas,Imad Derraz,Stephanos Finitsis,Jildaz Caroff,Romain Bourcier,Sébastien Soize,Solène Moulin,Sébastien Richard,Gaultier Marnat,Matúš Hoferica,Christophe Cognard,Jean‐Philippe Desilles,Mohammad Anadani,Jean‐Marc Olivot,Barbara Casolla,Arturo Consoli,Bertrand Lapergue,Benjamin Gory
出处
期刊:Journal of NeuroInterventional Surgery [BMJ]
卷期号:: jnis-021517
标识
DOI:10.1136/jnis-2024-021517
摘要

Background We evaluated the clinical and safety outcomes of emergent carotid artery stenting (eCAS) plus endovascular thrombectomy (EVT) among patients with anterior tandem lesion (TL) and large ischemic core (LIC). Methods This retrospective study included consecutive stroke patients enrolled in the Endovascular Treatment in Ischemic Stroke Registry in France between January 2015 and June 2023. We compared the outcomes of carotid stenting vs no stenting in tandem lesion with pre-treatment LIC (Alberta Stroke Program Early CT Score (ASPECTS) 3–5) and stenting in tandem lesion vs thrombectomy alone for isolated intracranial occlusions with pre-treatment LIC. Primary outcome was a score of 0 to 3 on the modified Rankin scale (mRS) at 90 days. Multivariable mixed-effects logistic regression was performed. Results Among 218 tandem patients with LIC, 55 were treated with eCAS plus EVT. The eCAS group had higher odds of 90-day mRS 0–3 (adjusted Odds Ratio (aOR) 2.40, 95% confidence interval (CI) 1.10 to 5.21; p=0.027). There were no differences in the risk of any intracerebral hemorrhage (OR 1.41, 95% CI 0.69 to 2.86; p=0.346), parenchymal hematoma (aOR 1.216, 95% CI 0.49 to 3.02; p=0.675), symptomatic intracerebral hemorrhage (aOR 1.45, 95% CI 0.60 to 3.48; p=0.409), or 90-day mortality (aOR 0.74, 95% CI 0.33 to 1.68; p=0.472). eCAS was associated with a higher rate of carotid patency at day 1 (aOR 3.54, 95% CI 1.14 to 11.01; p=0.028). Safety outcomes were similar between EVT+eCAS group in TL-LIC and EVT alone group in isolated intracranial occlusions with LIC. Conclusion eCAS appears to be a safe and effective strategy in patients with TL and LIC volume.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
xinxin发布了新的文献求助10
3秒前
3秒前
4秒前
小鱼完成签到,获得积分20
5秒前
5秒前
CodeCraft应助sbw采纳,获得10
6秒前
零一发布了新的文献求助10
10秒前
xinxin完成签到,获得积分10
10秒前
桑叶发布了新的文献求助10
10秒前
量子星尘发布了新的文献求助10
10秒前
傲娇衬衫发布了新的文献求助10
11秒前
Hello应助友好驳采纳,获得10
13秒前
阿桂发布了新的文献求助10
14秒前
15秒前
16秒前
Longfenzhong完成签到,获得积分10
16秒前
零一完成签到,获得积分10
16秒前
breaddog完成签到,获得积分10
17秒前
思源应助实验顺顺利利采纳,获得10
18秒前
迅速孤容完成签到 ,获得积分10
19秒前
19秒前
桑叶完成签到 ,获得积分10
19秒前
19秒前
GGKing完成签到,获得积分10
21秒前
研友_VZG7GZ应助傲娇衬衫采纳,获得10
22秒前
GGKing发布了新的文献求助10
23秒前
冰释发布了新的文献求助30
23秒前
wade发布了新的文献求助10
24秒前
谨言发布了新的文献求助10
25秒前
26秒前
文静紫霜完成签到,获得积分10
26秒前
慕青应助Glufo采纳,获得10
26秒前
28秒前
二喵完成签到 ,获得积分10
28秒前
澡雪发布了新的文献求助10
29秒前
coolru发布了新的文献求助100
30秒前
32秒前
33秒前
一顿吃不饱完成签到,获得积分0
34秒前
35秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 700
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3975755
求助须知:如何正确求助?哪些是违规求助? 3520108
关于积分的说明 11200829
捐赠科研通 3256492
什么是DOI,文献DOI怎么找? 1798298
邀请新用户注册赠送积分活动 877509
科研通“疑难数据库(出版商)”最低求助积分说明 806403