A photo-SAR study of photoswitchable azobenzene tubulin-inhibiting antimitotics identifying a general method for near-quantitative photocontrol

Azobenzene analogues of the tubulin polymerisation inhibitor combretastatin A4 ( PST s) were previously developed to optically control microtubule dynamics in living systems, with subsecond response time and single-cell spatial precision, by...