背景(考古学)
医学
叶状瘤
病理
纤维腺瘤
广谱
生物
内科学
乳腺癌
癌症
古生物学
化学
组合化学
作者
Farnaz Dadmanesh,Xiaomo Li,Matthew Leong,Horacio Maluf,Bonnie Balzer
出处
期刊:Advances in Anatomic Pathology
[Ovid Technologies (Wolters Kluwer)]
日期:2023-08-04
卷期号:30 (6): 415-420
被引量:1
标识
DOI:10.1097/pap.0000000000000407
摘要
Fibroepithelial lesions of the breast encompass a broad spectrum of lesions from fibroadenomas and their variants to phyllodes tumors, including their clinical range of benign, borderline, and malignant. Classification of this spectrum of neoplasms has historically and currently been based purely on morphology, although the nomenclature has shifted over the years largely due to the significant histologic overlap that exists primarily within the cellular fibroadenomas to borderline malignant phyllodes tumor categories. A review of the current diagnostic challenge, proposed ancillary studied and their value in prognostic significance, is provided. This article highlights the most recent molecular and genetic findings as well as the limitations of the studies, in the context of practical and available applications for the diagnostician and managerial implications for the clinician.
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