期刊:Science [American Association for the Advancement of Science (AAAS)] 日期:2018-01-11卷期号:359 (6372): 172.7-173
标识
DOI:10.1126/science.359.6372.172-g
摘要
DNA Damage
The kinase ATM coordinates the response to DNA damage. Lee et al. report that ATM also coordinates a response to oxidative stress that is independent of its response to DNA damage. Activation of ATM by oxidative stress promoted mitochondrial function and autophagy, thus enabling cell