医学
慢性血栓栓塞性肺高压
肺动脉高压
血栓栓塞性疾病
肺栓塞
心脏病学
内科学
心力衰竭
肺病
右心衰竭
血栓形成
标识
DOI:10.1016/j.ejim.2023.01.020
摘要
Patients with chronic thromboembolic pulmonary hypertension represent a subgroup of patients suffering from pulmonary hypertension. The disease is characterized by chronic, non-resolving thromboembolic obstruction of pulmonary arteries following one or more episodes of pulmonary embolism and involving both large vessel and small vessel dysfunction in the lungs [ [1] Piazza G. Goldhaber S.Z. Chronic thromboembolic pulmonary hypertension. N Engl J Med. 2011; 364: 351-360 Crossref PubMed Scopus (285) Google Scholar ]. Clinically, the most important manifestations are shortness of breath, fatigue and symptoms as a consequence of right sided heart failure, all resulting in a significantly affected quality of life and even enhanced mortality.
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