Selective Hydrofunctionalization of Alkenyl Fluorides Enabled by Nickel-Catalyzed Hydrogen Atoms and Group Transfer: Reaction Development and Mechanistic Study
化学
催化作用
群(周期表)
镍
氢
有机化学
作者
Fan Chen,Qianwei Zhang,Yingying Li,Zhi‐Xiang Yu,Lingling Chu
Due to the unique effect of fluorine atoms, the efficient construction of high-value alkyl fluorides has attracted significant interest in modern drug development. However, enantioselective catalytic strategies for the efficient assembly of highly functionalized chiral C(sp