Effects of different processing degrees of plant-based meat on the blood biochemical level, inflammation and intestinal microorganisms in mice

In recent years, with the increasing health needs of people, plant-based meat products have gradually entered the public's vision. However, many plant-based meats on the market today are so heavily processed and use so many additives that they can be classified as ultra-processed foods (UPFs). Very limited studies report whether the benefits of these plant-based meats are discounted when lots of additives were added. In this experiment, mice were fed with processed plant-based meat, ultra-processed plant-based meat, low-processed red meat, ultra-processed red meat to compare the health effects. In this experiment, some serum biochemical indexes, hematoxylin-eosin (HE) staining of liver and intestine, 16s rDNA and short-chain fatty acids of mouse feces were detected. Compared with the negative control group, it was found that mice in the ultra-processed plant-based meat group, ultra-processed red meat group, and low-processed red meat group gained significant weight, and there exist intestinal inflammation and liver inflammation. In terms of gut microbiota, the diversity and structure of gut microbiota in both two plant-meat group was better than that in both two red-meat group. It can be concluded that plant-based meat and red meat cause different gut microbiota outcomes, which in turn affect body weight and the occurrence of liver and intestinal inflammation. What's more, plant-based meat is healthier than red meat, but overprocessing reduces the benefits of plant-based meat. There is a need to improve the way plant-based meat is processed and reduce the amount of additives used.