Palladium-catalyzed dearomative Heck/[4 + 3] decarboxylative cyclization of indoles with α-oxocarboxylic acids via C−H activation
化学
催化作用
钯
脱羧
赫克反应
组合化学
药物化学
吲哚试验
有机化学
作者
Liwei Zhou,Pengyang Jing,Wenbo Deng,Shuyi Guo,Yun Liang,Yuan Yang
出处
期刊:Organic chemistry frontiers [The Royal Society of Chemistry] 日期:2024-12-19
标识
DOI:10.1039/d4qo02024c
摘要
Herein, we report a novel palladium-catalyzed dearomative Heck/[4 + 3] decarboxylative cyclization of C2-tethered indoles with α-oxocarboxylic acids via C−H activation. In this reaction, dearomatization of C2-tethered indoles occurs via...