Predictive Value of the Naples Prognostic Score for Cardiovascular Outcomes in Patients With Chronic Kidney Disease Receiving Percutaneous Coronary Intervention

狼牙棒 医学 传统PCI 经皮冠状动脉介入治疗 内科学 危险系数 肾脏疾病 比例危险模型 临床终点 入射(几何) 回顾性队列研究 风险因素 心脏病学 置信区间 心肌梗塞 随机对照试验 光学 物理
作者
Xue Zhang,Jingkun Zhang,Xue Wu,Xing Liu,Tong Liu,Kang‐Yin Chen
出处
期刊:Angiology [SAGE Publishing]
被引量:5
标识
DOI:10.1177/00033197241285970
摘要

The Naples prognostic score (NPS) is a novel multidimensional inflammatory and nutritional assessment system in cancer patients. However, its significance in patients with chronic kidney disease (CKD) after percutaneous coronary intervention (PCI) remains unclear. The study has a single-center, retrospective design and included 631 patients with CKD who underwent index PCI between 2019 and 2022. All participants were divided into 2 groups according to the NPS (Low-risk group: n = 209; High-risk group: n = 422) and followed up until November 2022. The primary endpoint was Major Adverse Cardiac Events (MACE). NPS predicted MACE events better than other scores, besides, high-risk NPS with severe renal dysfunction (RD) group (MODEL 2) had superior MACE diagnostic efficiency than NPS high-risk group lonely. (NPS: AUC: 0.605, P < .001; MODEL 2: AUC: 0.624, P < .001, respectively). Kaplan–Meier survival analysis of two groups showed that high-risk group had higher incidence of MACE ( P < .001). Meanwhile, high-risk group had higher MACE events [adjusted Hazard Ratio (aHR) 2.013, 95% CI 1.294, 3.132; P = .002]. NPS is an independent prognostic factor for CKD patients undergoing index PCI before operation whose predictive value for survival prognosis is better than other nutritional and inflammatory indicators. Compared with low NPS, patients with high NPS have a relatively poor prognosis.
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