作者
Danlei Zhou,Emily King,Simon Rothwell,Olga Kryštůfková,Antonella Notarnicola,Samantha Coss,Rabheh Abdul‐Aziz,Katherine E. Miller,Amanda Dang,Gakit Richard Yu,Joanne Drew,Emeli Lundström,Lauren M. Pachman,Gulnara Mamyrova,Rodolfo Curiel,Boél De Paepe,Jan De Bleecker,Antony Payton,William Ollier,Terrance P. OʼHanlon,Ira N. Targoff,Willy A. Flegel,Vidya Sivaraman,Edward J. Oberle,Shoghik Akoghlanian,Kyla Driest,Charles H. Spencer,Yee Ling Wu,Haikady N. Nagaraja,Stacy P. Ardoin,Hector Chinoy,Lisa G. Rider,Frederick W. Miller,Ingrid E. Lundberg,Leonid Padyukov,Jiří Vencovský,Janine A. Lamb,C. Yung Yu
摘要
Idiopathic inflammatory myopathies (IIM) are a group of autoimmune diseases characterised by myositis-related autoantibodies plus infiltration of leucocytes into muscles and/or the skin, leading to the destruction of blood vessels and muscle fibres, chronic weakness and fatigue. While complement-mediated destruction of capillary endothelia is implicated in paediatric and adult dermatomyositis, the complex diversity of complement