蛋白酵素
病毒进入
TMPRS2型
病毒
生物
组织蛋白酶L
细胞生物学
病毒学
分子生物学
酶
病毒复制
生物化学
2019年冠状病毒病(COVID-19)
医学
疾病
病理
传染病(医学专业)
作者
Hui Yang,Junnian Zhou,Xuemei Zhang,Dandan Ling,Ying‐Bao Sun,Chen‐Yan Li,Qian‐Qian Zhou,Gaona Shi,S. Q. Wang,Xiao‐Song Lin,Tao Fan,Haiyang Wang,Quan Zeng,Yi Jia,Jiafei Xi,Yi‐Guang Jin,Xuetao Pei,Wen Yue
标识
DOI:10.1002/adma.202310306
摘要
The enzymatic activities of Furin, Transmembrane serine proteinase 2 (TMPRSS2), Cathepsin L (CTSL), and Angiotensin-converting enzyme 2 (ACE2) receptor binding are necessary for the entry of coronaviruses into host cells. Precise inhibition of these key proteases in ACE2
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