Eperisone hydrochloride in treating tension-type headache with depression and/or anxiety

Objective To research effective methods of treating tension-type headache with depression and/or anxiety.Methods One hundred and thirty-six tension-type headache cases with depression and/or anxiety were divided into two groups randomly,which included drug group treated with eperisone hydrochloride and anti-depression drug,and control group treated with anti-depression drug only.Assessed the curative effect after 2 weeks and 4 weeks treating.Results The frequency decreased,persistence time shortened and degree lessened in drug group of headache(2 weeks P＜0.05,4 weeks P＜0.01).And eperisone hydrochloride also decreased HAMD(2 weeks and 4 weeks P＜0.01)and HAMA(2 weeks P＜0.05,4 weeks P＜0.01).Conclusions The therapeutic effect of eperisone hydrochloride in tension-type headache with depression and/or anxiety is significant. Key words: Eperisone hydrochloride; Tension-type headache; Depression; Anxiety