磺胺
化学
抗菌剂
过渡金属
金属
苯
催化作用
组合化学
药物化学
有机化学
作者
Muhammad Pervaiz,Aqsa Riaz,Anfal Munir,Zohaib Saeed,Shah Hussain,Ayoub Rashid,Umar Younas,Ahmad Adnan
标识
DOI:10.1016/j.molstruc.2019.127284
摘要
The sulfa drug ligands and their derivatives retain well-thought-out as pre-eminent compounds in the field of synthetic as well as pharmaceutical chemistry. The transition metal complexes of 4-amino-N-(5-methyl-3-isoxazolyl)benzene sulfonamide are synthesized by reaction of 4-amino-N-(5-methyl-3-isoxazolyl)benzene sulfonamide with metals like Mn(II), Co(II), Fe(II), Fe(III),Cr(III),Ni(II),Cu(II) and Zn(II).The synthesized metal complexes of sulfa drugs have been engaged for biological (as anti-bacterial &anti-fungal entities) as well as catalytic activity as example Olefin Polymerization. Due to broad spectrum range, the sulfa drug derived complexes are found to be very imperative in pharmaceutical and medical chemistry. Being borne in mind the worth of sulfa drug based transition metal complexes, the review has recapitulated the synthesis, characterization and antimicrobial activities of 4-amino-N-(5-methyl-3-isoxazolyl) benzene sulfonamide metal complexes.
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