Bis(2-methoxyethyl)ether promoted intramolecular acceptorless dehydrogenative coupling to construct structurally diverse quinazolinones by molecular oxygen

A simple, efficient and clean intramolecular oxidative dehydrogenative coupling for the synthesis of dihydroisoquinolino[2,1- a ]quinazolinones, 2-aryl quinazolinones, and analogues promoted by bis(2-methoxyethyl)ether/O 2 has been achieved.