分子内力
化学
催化作用
区域选择性
药物化学
分子内反应
立体化学
组合化学
有机化学
作者
Pardeep Dahiya,Ankita Sarkar,Basker Sundararaju
标识
DOI:10.1002/adsc.202200385
摘要
Abstract We present an efficient method for forming C−N bonds via intramolecular amidation catalyzed by well‐defined Cp*Co(N,O)I complexes. The reaction has been operate under mild conditions and produced a regioselective amidation product without the use of a bulky counter anion or expensive fluorinated solvents. The Cp*Co(N,O)‐I catalyst is very effective for intramolecular benzylic, tertiary, and internal C( sp 3 )−H bond amidation, but ineffective for intramolecular C( sp 2 )−H bond amidation. magnified image
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