医学
特发性肺纤维化
肺纤维化
磷酸二酯酶抑制剂
内科学
磷酸二酯酶
cGMP特异性磷酸二酯酶5型
药理学
化学
纤维化
西地那非
肺
生物化学
酶
作者
Luca Richeldi,Arata Azuma,Vincent Cottin,Christian Heßlinger,Susanne Stowasser,Claudia Valenzuela,Marlies Wijsenbeek,Donald F. Zoz,Florian Voß,Toby M. Maher
标识
DOI:10.1056/nejmoa2201737
摘要
In this placebo-controlled trial, treatment with BI 1015550, either alone or with background use of an antifibrotic agent, prevented a decrease in lung function in patients with idiopathic pulmonary fibrosis. (Funded by Boehringer Ingelheim; 1305-0013 ClinicalTrials.gov number, NCT04419506.).
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