Progress of homogeneous and heterogeneous electro-Fenton treatments of antibiotics in synthetic and real wastewaters. A critical review on the period 2017–2021

Antibiotics are widely supplied over all the world to animals and humans to fight and heal bacteriological diseases. The uptake of antibiotics has largely increased the average-life expectancy of living beings. However, these recalcitrant products have been detected at low concentrations in natural waters, with potential health risks due to alterations in food chains and an increase in the resistance to bacterial infection, control of infectious diseases, and damage of the beneficial bacteria. The high stability of antibiotics at mild conditions prevents their effective removal in conventional wastewater treatment plants. A powerful advanced oxidation processes such as the electro-Fenton (EF) process is being developed as a guarantee for their destruction by •OH generated as strong oxidant. This review presents a critical, exhaustive, and detailed analysis on the application of EF to remediate synthetic and real wastewaters contaminated with common antibiotics, covering the period 2017-2021. Homogeneous EF and heterogeneous EF involving iron solid catalysts or iron functionalized cathodes, as well as their hybrid and sequential treatments, are exhaustively examined. Their fundamentals and characteristics are detailed, and the main results obtained for the removal of the most used antibiotic families are carefully described and discussed. The role of generated oxidizing agents is explained, and the by-products generated, and reaction sequences proposed are detailed.