生物
月经
子宫内膜
巨噬细胞
表型
疾病
月经周期
功能(生物学)
怀孕
生理学
免疫学
细胞生物学
内科学
内分泌学
体外
医学
基因
遗传学
激素
作者
Erin Brown,Rocío Martínez-Aguilar,Jacqueline A. Maybin,Douglas A Gibson
标识
DOI:10.1016/bs.ircmb.2022.03.011
摘要
Macrophages are present in the endometrium throughout the menstrual cycle and are most abundant during menstruation. Endometrial macrophages contribute to tissue remodeling during establishment of pregnancy and are thought to play key roles in mediating tissue breakdown and repair during menstruation. Despite these important roles, the phenotype and function of endometrial macrophages remains poorly understood. In this review, we summarize approaches used to characterize endometrial macrophage phenotype, current understanding of the functional role of macrophages in normal endometrial physiology as well as the putative contribution of macrophage dysfunction to women's reproductive health disorders.
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