光子学
谐振器
绝缘体上的硅
纳米技术
硅
制作
波导管
灵敏度(控制系统)
材料科学
硅光子学
光电子学
CMOS芯片
生物传感器
表面改性
检出限
电子工程
化学
工程类
机械工程
医学
替代医学
病理
色谱法
作者
Patrick Steglich,Dominik G. Rabus,C. Sada,Martin Paul,Michael G. Weller,Christian Mai,Andreas Mai
出处
期刊:IEEE Sensors Journal
[Institute of Electrical and Electronics Engineers]
日期:2022-06-01
卷期号:22 (11): 10089-10105
被引量:18
标识
DOI:10.1109/jsen.2021.3119547
摘要
Silicon photonic micro-ring resonators (MRR) developed on the silicon-on-insulator (SOI) platform, owing to their high sensitivity and small footprint, show great potential for many chemical and biological sensing applications such as label-free detection in environmental monitoring, biomedical engineering, and food analysis. In this tutorial, we provide the theoretical background and give design guidelines for SOI-based MRR as well as examples of surface functionalization procedures for label-free detection of molecules. After introducing the advantages and perspectives of MRR, fundamentals of MRR are described in detail, followed by an introduction to the fabrication methods, which are based on a complementary metal-oxide semiconductor (CMOS) technology. Optimization of MRR for chemical and biological sensing is provided, with special emphasis on the optimization of waveguide geometry. At this point, the difference between chemical bulk sensing and label-free surface sensing is explained, and definitions like waveguide sensitivity, ring sensitivity, overall sensitivity as well as the limit of detection (LoD) of MRR are introduced. Further, we show and explain chemical bulk sensing of sodium chloride (NaCl) in water and provide a recipe for label-free surface sensing.
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