甲基苯丙胺
静息状态功能磁共振成像
心理学
神经科学
禁欲
功能连接
默认模式网络
注意力网络
上瘾
精神科
计算机科学
人工智能
作者
Meysam Siyah Mansoory,Armin Allahverdy,Maryam Behboudi,Mehdi Khodamoradi
标识
DOI:10.1016/j.bbr.2022.114022
摘要
This study set out to assess restingstate functional connectivity (rs-FN) and graph theorybased local efficiency within the left and right hemispheres of methamphetamine (MA) users. Functional brain networks of 19 MA users and 21 control participants were analyzed using restingstate fMRI. Graph edges in functional networks of the brain were defined and recurrence plot was used. We found that MA abuse may be accompanied by alterations of rs-FN within the defaultmode network (DMN), executive control network (ECN), and the salience network (SN) in both hemispheres of the brain. Moreover, we observed that such effects of MA may be correlated with duration of MA abuse and MA abstinence in many components of the DMN and SN. The results would seem to suggest that MAinduced alterations of local efficiency may, in part, account for maladaptive decision making, deficits in executive function and control over drug seeking/taking, and relapse.
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