Large cell lymphoma-like reaction in a cervical polyp

Inflammatory lesions of the uterine cervix are very common, and although lymphomas in this location are rare, the differential diagnosis between both diseases must be considered in some cases and may be difficult to achieve.A 37-year-old woman in good health with a cervical polyp, showing a lymphoma-like reaction with blastic appearance, which was initially interpreted as a diffuse large-cell lymphoma. The immunohistochemical and molecular studies showed the reactive origin of the lesion.Immunohistochemical and molecular biology studies may be useful to dilucidate the reactive or neoplastic origin of these lesions.