软骨寡聚基质蛋白
骨关节炎
生物标志物
医学
软骨
发病机制
生物信息学
病理
生物
解剖
遗传学
替代医学
作者
Lunhao Bai,Yu Wang,Tianpeng Zhang
出处
期刊:Chinese Journal of Reparative and Reconstructive Surgery
日期:2010-06-01
卷期号:24 (6): 714-717
被引量:1
摘要
Objective To review the research progress of cartilage oligomeric matrix protein (COMP). Methods Domestic and abroad literature about COMP was reviewed and summarized. Results COMP was one of the osteoarthritis (OA) biomarkers of being widely studied. Most studies in recent years could draw the conclusion that COMP was associated with OA. COMP was the foremost biomarker among investigated biomarkers. It could been continuously expressed and predicted knee OA progression. Conclusion Precisely what role COMP plays in OA pathogenesis remains unclear, using COMP as a tool to early diagnose OA more studies would be needed.
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