烯烃
化学
醛
亲核细胞
试剂
亲核加成
有机化学
酒
组合化学
光化学
催化作用
作者
D. Hu,Huu Phuong Dang,Yong‐Min Liang,Donghao Wang,Yunyun Du,Chao Shen,Jiabin Shen,Min Wang
标识
DOI:10.1021/acs.orglett.4c03819
摘要
Herein, a photocatalytic strategy for the synthesis of secondary alcohols by nucleophilic addition of an alkene with an aldehyde is described. This operationally simple methodology opens an approach for the synthesis of alcohols using commercially available reagents in moderate to excellent yields. Mechanistic studies indicate that the formation of the radical anion from alkene via single-electron transfer is the key step in this reaction.
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