The potential of salivary albumin to degrade composite resin

唾液 白蛋白 努氏硬度试验 化学 复合数 抗弯强度 压痕硬度 核化学 色谱法 牙科 复合材料 材料科学 生物化学 医学 结晶学 微观结构
作者
Leonardo Santos de Barros,Giovanna Corrêa Denucci,Flávia Lucisano Botelho do Amaral,Fabiana Mantovani Gomes França,Roberta Tarkany Basting,Cecília Pedroso Turssi
出处
期刊:Acta odontológica latinoamericana 卷期号:36 (1): 34-39
标识
DOI:10.54589/aol.36/1/34
摘要

Albumin is a salivary enzyme capable of cleaving ester linkages and catalyzing degradation of resin-based dental materials. However, the effect of concentration-dependent esterolytic action on composite resins as yet remains unexplored.The purpose of this study was to evaluate whether artificial saliva formulations with different concentrations of albumin affected the surface roughness, flexural strength and microhardness of a composite resin.Specimens (25x2x2mm) of a nanofilled composite (Filtek Z350XT, 3M/ESPE) were prepared and analyzed for average surface roughness (Ra/pm). The specimens were then allocated to 6 groups (n=30), to be treated with different salivary albumin concentrations: 0, 10, 50, 100, 200, 400 pg/mL. The specimens were stored in their respective artificial saliva groups, half of them for 24 h and the remainder for 180 days (artificial saliva renewed weekly), after which they were submitted to a new Ra reading, and tested for three-point flexural strength (FS, MPa). The specimens stored for 180 days were analyzed for Knoop microhardness (KH, Kg/mm2). Data were submitted to two-way ANOVA (Ra and FS) and one-way ANOVA (KH).Although Ra increased (p < 0.001) and FS decreased (p < 0.001) from 24 hours to 180 days of storage, the albumin concentration did not significantly affectRa (p = 0.168), FS (p = 0.477) or KH (p = 0.378).The esterolytic action of albumin did not increase the artificial-saliva-induced hydrolytic degradation of the composite resin.Albumina, uma enzima encontrada na saliva, é capaz de clivar ligagoes éster e catalisar a degradando de materiais dentários á base resina. Apesar da agao esterolítica ser potencialmente concentragao-dependente, a investigando desse efeito sobre resinas compostas ainda permanence inexplorado. Objetivo: O objetivo deste estudo foi avaliar se formulagoes de saliva artificial contendo diferentes concentragoes de albumina afetariam a rugosidade superficial, a resistencia flexural e a microdureza de uma resina composta. Materials e Método: Corpos de pro-va em barra (25x2x2mm) foram confeccionados a partir de uma resina composta nanoparticulada (Filtek Z350XT, 3M/ESPE) e foram submetidos á leitura de rugosidade superficial média inicial (Ra, pm), em rugosímetro. Entao, as amostras foram divididas em 6 grupos (n=30) de acordo com a concentrando de albumina na saliva: 0, 10, 50, 100, 200, 400 pg/mL. As amostras foram armazenadas nas formulagoes de saliva artificial correspondente ao seu grupo, metade por 24 h e as demais por 180 dias (com trocas de saliva semanais). As amostras foram submetidas a no-vas leituras de rugosidade (Rafinal) e avaliadas quanto á resistencia flexural de tres pontos (RF, MPa). As amostras armazenadas por 180 dias foram avaliadas quanto á microdureza Knoop (KH, Kg/mm2). Os dados foram submetidos a análises de variáncia a dois critérios (Ra e RF) e a um critério (KH). Resultados: Apesar de haver aumento na Ra (p < 0,001) e uma diminuigao da RF (p < 0,001) de 24 h para 180 dias, a concentragao de albumina nao afetou significativamente a Ra (p = 0,168), a RF (p = 0,477) ou a KH (p = 0,378). Conclusoes: A agdo esterolítica da albumina nao aumentou a degradagao hidrolítica da resina composta induzida pela saliva artificial.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
深情安青应助科研通管家采纳,获得10
刚刚
科研通AI5应助科研通管家采纳,获得10
刚刚
今后应助科研通管家采纳,获得10
刚刚
Orange应助科研通管家采纳,获得10
刚刚
慕青应助科研通管家采纳,获得10
刚刚
科研通AI2S应助科研通管家采纳,获得10
刚刚
刚刚
诚心的醉卉完成签到,获得积分10
刚刚
刚刚
hoshi完成签到,获得积分10
刚刚
汉堡包应助hhhbbb采纳,获得10
1秒前
乐乐应助wjx采纳,获得10
1秒前
傅宛白发布了新的文献求助10
1秒前
受伤的无敌完成签到,获得积分10
2秒前
玩命做科研给玩命做科研的求助进行了留言
3秒前
勤劳初雪应助嘻嘻嘻采纳,获得10
3秒前
蓝色牛马发布了新的文献求助10
3秒前
4秒前
4秒前
平淡凡柔发布了新的文献求助10
5秒前
苗条的善斓完成签到,获得积分10
5秒前
田様应助GAOBIN000采纳,获得10
5秒前
6秒前
江上清风游完成签到,获得积分10
6秒前
LiDaYang完成签到,获得积分10
6秒前
lii完成签到,获得积分10
6秒前
充电宝应助DDDANDUDU采纳,获得10
6秒前
7秒前
香蕉觅云应助满当当采纳,获得10
7秒前
赘婿应助LLL采纳,获得10
7秒前
xzf1996完成签到,获得积分10
8秒前
淡然紫寒完成签到,获得积分20
8秒前
莫宛完成签到,获得积分10
8秒前
眼睛大行云完成签到,获得积分10
8秒前
芮rich完成签到,获得积分10
8秒前
8秒前
明理的问柳完成签到 ,获得积分10
8秒前
8秒前
lelele完成签到,获得积分10
9秒前
从前的我完成签到,获得积分10
9秒前
高分求助中
(应助此贴封号)【重要!!请各用户(尤其是新用户)详细阅读】【科研通的精品贴汇总】 10000
Manipulating the Mouse Embryo: A Laboratory Manual, Fourth Edition 1000
Comparison of spinal anesthesia and general anesthesia in total hip and total knee arthroplasty: a meta-analysis and systematic review 500
INQUIRY-BASED PEDAGOGY TO SUPPORT STEM LEARNING AND 21ST CENTURY SKILLS: PREPARING NEW TEACHERS TO IMPLEMENT PROJECT AND PROBLEM-BASED LEARNING 500
Founding Fathers The Shaping of America 500
Distinct Aggregation Behaviors and Rheological Responses of Two Terminally Functionalized Polyisoprenes with Different Quadruple Hydrogen Bonding Motifs 460
Writing to the Rhythm of Labor Cultural Politics of the Chinese Revolution, 1942–1976 300
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 纳米技术 计算机科学 内科学 化学工程 复合材料 物理化学 基因 催化作用 遗传学 冶金 电极 光电子学
热门帖子
关注 科研通微信公众号,转发送积分 4572422
求助须知:如何正确求助?哪些是违规求助? 3993137
关于积分的说明 12361436
捐赠科研通 3666284
什么是DOI,文献DOI怎么找? 2020629
邀请新用户注册赠送积分活动 1054898
科研通“疑难数据库(出版商)”最低求助积分说明 942305