Emerging role of pericyte-expressed circPLOD2 in the regulation of capillary stability

Glaser and colleagues characterized hypoxia-regulated circRNAs in pericytes and revealed the role of circPLOD2 in pericyte biology, endothelial-pericyte interactions, and vascular network formation.1 Understanding circPLOD2-regulatory network helps identify novel interventions to improve capillary growth and stability.