Erythrodermic Bullous Pemphigoid in Skin of Color Treated With Dupilumab

Bullous pemphigoid (BP) is an autoimmune blistering disease that typically presents with pruritic, tense bullae in elderly patients.1 Several recognized presentations deviate from the classic bullous eruption, and erythrodermic BP, in particular, is thought to be a rare phenomenon. Herein, we present a case of erythrodermic BP in an African American male who initially presented with erythroderma in the absence of tense bullae. There have been no reports on erythrodermic BP in skin of color to our knowledge. The patient rapidly improved after treatment was started with dupilumab. He developed classic tense bullae seen in BP once dupilumab was discontinued.Sanfilippo E, Gonzalez Lopez A, Saardi KM. Erythrodermic bullous pemphigoid in skin of color treated with dupilumab. J Drugs Dermatol. 2023;22(7):685-686. doi:10.36849/JDD.7196.