17th German Spine Congress, Annual Meeting of the German Spine Society

Background: This prospective study investigates the influencing factors: depression, duration of symptoms, body weight and age on PROMs in spine surgery.Methods: PROMs evaluating spine function (Oswestry Disability Index ODI, Core Outcome Measures Index COMI, Subjective Spine Value SSpV) and PROMs assessing health-related quality of life EQ-5D-5L, EQ-VAS and Patient Reported Outcomes Measurement Information System PROMIS-29 were collected in 160 patients pre-as well as post-operatively at 6 weeks, 3 months, 6 months and one year.The influence of existing depression, duration of symptoms, overweight and age is investigated by multiple analysis of variance.Results: Pre-existing preoperative depression does not influence PROMs assessing spinal function, (SSpV (p=0.645),ODI (p=0.437),COMI (p= 0.179).General health-related quality of life is impaired in the qualities of sleep, fatigue, anxiety, and depression by 0.6-2 standard deviations (p<= 0.001).For suffering less than 3 months, ODI, COMI, pain impairment and physical function showed better results postoperatively (p<0.05).Chronic complaints showed significant impairment in overall health-related quality of life (p<0.05).Normal weight patients showed a faster improvement in spinal function (p<0.05).Body weight did not affect PROMs of healthrelated quality of life.Younger patients showed better results earlier than older patients for both PROMs of spine function and PROMs of health-related quality of life (p<0.05).Discussion: Health-related quality of life is affected by spinal function.Pre-existing depression does not affect spinal function or its measurement tools.Younger and normal weight patients showed earlier convalescence.Chronic discomfort permanently impairs health-related quality of life and decreases postoperative spinal function.The negative influence of the duration of discomfort on PROMs, points to the relevance of the indication.The results point out the special requirements of postoperative treatment in frail (elderly, overweight) patients.The findings of the study have clinical relevance for surgical education and patient information.