微生物群
肠道微生物群
毒力
抗菌剂
微生物学
肝硬化
医学
生物
生物信息学
内科学
遗传学
基因
作者
Sunjae Lee,Bethlehem Arefaine,Neelu Begum,Marilena Stamouli,Elizabeth A. Witherden,Merianne Mohamad,Azadeh Harzandi,Ane Zamalloa,Haizhuang Cai,Roger Williams,Michael A. Curtis,Lindsey Edwards,Shilpa Chokshi,Adil Mardinoğlu,Gordon Proctor,David L. Moyes,Mark McPhail,Debbie L. Shawcross,Mathias Uhlén,Saeed Shoaie,Vishal Patel
标识
DOI:10.1016/j.jhep.2024.09.046
摘要
Cirrhosis complications are often triggered by bacterial infections with multidrug-resistant organisms. Alterations in the gut and oral microbiome in decompensated cirrhosis (DC) influence clinical outcomes. We interrogated: (i) gut and oral microbiome community structures, (ii) virulence factors (VFs) and antimicrobial resistance genes (ARGs) and (iii) oral-gut microbial overlap in patients with differing cirrhosis severity.
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