Advancements in Electrochemical Immunosensors Towards Point-of-care Detection of Cardiac Biomarkers

检测点注意事项 注意事项 电化学 化学 点(几何) 纳米技术 医学 计算机科学 材料科学 病理 数学 电极 物理化学 几何学
作者
Sasya Madhurantakam,Bianca Elizabeth David,Aliya Naqvi,Zachary Lee,Jacob Thomas Abraham,Trayi Sai Vankamamidi,Shalini Prasad
出处
期刊:Analytical Methods [The Royal Society of Chemistry]
卷期号:16 (39): 6615-6633 被引量:2
标识
DOI:10.1039/d4ay01049c
摘要

Cardiovascular disease remains the leading cause of death worldwide, with mortality rates increasing annually. This underscores the urgent need for accurate diagnostic and monitoring tools. Electrochemical detection has emerged as a promising method for swiftly and precisely measuring specific biomarkers in bodily fluids. This approach is not only cost-effective and efficient compared to traditional clinical methods, but it can also be tailored to detect individual biomarkers, which makes it particularly well-suited for point-of-care (POC) applications. The ability to conduct testing at the point of care is crucial for timely interventions and personalized disease management, empowering healthcare providers to tailor treatment plans based on real-time biomarker data. Thanks to recent advancements in nanomaterials, we've seen significant progress in electrochemical detection, leading to the development of specialized rapid immunoassay systems. These systems utilize specific antibodies to target molecules, expanding the range of detectable biomarkers. This innovation has the potential to revolutionize the diagnosis and treatment of cardiovascular diseases by enhancing detection sensitivity and specificity. Ultimately, these advancements aim to improve patient outcomes by enabling earlier diagnosis, more precise monitoring, and personalized therapeutic interventions, which will contribute to more effective management of cardiovascular health globally.
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