亲爱的研友该休息了!由于当前在线用户较少,发布求助请尽量完整地填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!身体可是革命的本钱,早点休息,好梦!

Incidence, risk factors, and outcomes of recurrent focal segmental glomerulosclerosis in pediatric kidney transplant recipients: A systematic review and meta‐analysis

医学 局灶节段性肾小球硬化 移植 肾移植 入射(几何) 肾脏疾病 风险因素 内科学 儿科 外科 泌尿科 肾小球肾炎 物理 光学
作者
Jiang Bai,Xinyu Yin,Jiaqi Li,Jiaqi Li,Y.-L. Niu,Zhenhua Li,Jing Li,Yun Zhou
出处
期刊:Clinical transplantation [Wiley]
卷期号:37 (11) 被引量:2
标识
DOI:10.1111/ctr.15119
摘要

Abstract Background Focal segmental glomerulosclerosis is the most prevalent acquired kidney disease leading to end‐stage renal disease in children and has a propensity for recurring in the transplanted kidney. The recurrence of FSGS after kidney transplantation in children varies greatly. In addition, the risk factors and outcomes of recurrence of FSGS remain controversial. This study evaluated the recurrence rate, risk factors, and prognosis of FSGS after kidney transplantation in order to provide advice and assistance in clinical decision‐making for pediatric kidney transplantation. Methods PubMed, Embase, Web of Science, CNKI, and other databases were searched from the establishment of the repository to March 2022. We extracted data on incidence, risk factors, and outcomes. Results The results showed that the recurrence rate of primary FSGS in children after renal transplantation was 48% (95% CI 36%–59%) and the recurrence rate of FSGS (all forms) was 35% (95% CI 17%–52%). The graft loss rate of primary FSGS in children after kidney transplantation was 29% (95% CI 17%–42%) and the graft loss rate of FSGS (all forms) was 29% (95% CI 4%–62%). 57% (95% CI 42%–73%) of pediatric patients with recurrent primary FSGS showed complete remission. Risk factor analyses showed that age of onset (SMD .69, 95% CI .20–1.19, p = .006) was related to the recurrence of primary FSGS, whereas the living related donor was not a risk factor for recurrent primary FSGS in pediatrics after kidney transplantation (OR 1.22, 95% CI .48–3.10, p = .674). Conclusions The recurrence rate and graft loss rate of FSGS in children after kidney transplantation were relatively high. Age at onset was associated with a risk for recurrent primary FSGS, whereas the living related donor was not a risk factor for recurrent FSGS in pediatric kidney recipients.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
Perry完成签到,获得积分10
23秒前
江枫渔火完成签到 ,获得积分10
31秒前
MchemG应助科研通管家采纳,获得10
1分钟前
闫雪完成签到,获得积分10
1分钟前
1分钟前
闫雪发布了新的文献求助10
1分钟前
Plum22发布了新的文献求助20
1分钟前
直觉应助闫雪采纳,获得10
1分钟前
蚂蚁踢大象完成签到 ,获得积分10
2分钟前
hgsgeospan完成签到,获得积分10
2分钟前
直率的笑翠完成签到 ,获得积分10
2分钟前
hgs完成签到,获得积分10
2分钟前
2分钟前
MchemG应助科研通管家采纳,获得10
3分钟前
JamesPei应助科研通管家采纳,获得10
3分钟前
隐形曼青应助科研通管家采纳,获得10
3分钟前
Kevin完成签到,获得积分10
3分钟前
3分钟前
辉哥发布了新的文献求助10
3分钟前
4分钟前
4分钟前
董可以发布了新的文献求助10
4分钟前
英俊的铭应助董可以采纳,获得10
4分钟前
curtain完成签到,获得积分10
4分钟前
大个应助科研通管家采纳,获得10
5分钟前
MchemG应助科研通管家采纳,获得10
5分钟前
所所应助科研通管家采纳,获得10
5分钟前
科研通AI2S应助科研通管家采纳,获得10
5分钟前
5分钟前
落寞书易完成签到 ,获得积分10
5分钟前
5分钟前
现实的小霸王完成签到,获得积分10
5分钟前
5分钟前
Xw完成签到,获得积分10
6分钟前
科研通AI5应助迷人问兰采纳,获得10
6分钟前
Hello应助LSH970829采纳,获得10
6分钟前
Xw发布了新的文献求助10
6分钟前
寒冷的应助核桃采纳,获得30
6分钟前
wen发布了新的文献求助10
7分钟前
隐形曼青应助科研通管家采纳,获得10
7分钟前
高分求助中
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3990084
求助须知:如何正确求助?哪些是违规求助? 3532108
关于积分的说明 11256447
捐赠科研通 3271016
什么是DOI,文献DOI怎么找? 1805171
邀请新用户注册赠送积分活动 882270
科研通“疑难数据库(出版商)”最低求助积分说明 809228