[Analysis of mortality trend and characteristic of chronic obstructive pulmonary disease among residents in China from 2004 to 2020].

Objective: To analyze the mortality trend and characteristics of chronic obstructive pulmonary disease (COPD) among residents in China from 2004 to 2020. Methods: From the area, gender, region, and age dimensions, the Joinpoint regression model was used to analyze the trend of COPD mortality rate from 2004 to 2020, extracted from the China Death Surveillance Dataset. Results: From 2004 to 2020, the mortality rate and age-adjusted mortality rate of COPD showed a downward trend (AAPC=-3.68%, P<0.001; AAPC=-7.27%, P<0.001), which were consistent with urban and rural subpopulations (mortality rate: AAPC=-3.62%, P=0.009, AAPC=-3.23%, P=0.014; age-adjusted mortality rate: AAPC=-7.26%, P<0.001, AAPC=-6.78%, P<0.001). The mortality rate of COPD in rural was higher than that of urban subpopulations (P<0.001). Also, the mortality rate and age-adjusted mortality rate of COPD showed a downward trend in males and females (mortality rate: AAPC=-3.00%, P<0.001, AAPC=-4.37%, P<0.001; age-adjusted mortality rate: AAPC=-6.73%, P<0.001, AAPC=-8.11%, P<0.001), and the COPD mortality rate for male was generally higher than female (P<0.001). Meanwhile, the mortality rate of COPD in eastern, central and western regions also showed a downward trend (AAPC=-3.87%, P<0.001; AAPC=-3.12%, P<0.001; AAPC=-1.37%, P=0.001), and western regions were significantly higher than that in central (P<0.001) and eastern (P<0.001) regions. The mortality rate of COPD in the age group of Chinese people showed a downward trend in<45, 45-59, and≥60 years groups (AAPC=-9.48%, P<0.001; AAPC=-9.03%, P<0.001; AAPC=-5.91%, P<0.001). Among them,≥60 years groups was significantly higher than that in<45 (P<0.001) and 45-59 (P<0.001) years groups, and the decline rate was slowest. Conclusion: In China, the mortality rate of COPD decreases from 2004 to 2020, and more efforts are needed to reduce COPD mortality, especially in western regions, rural populations, males and the elderly.目的： 分析2004—2020年我国居民慢性阻塞性肺疾病（COPD）死亡趋势及其特征。 方法： 从《中国死因监测数据集》中获取2004—2020年我国居民COPD死因监测数据，从城乡、性别、地区和年龄四个维度，采用Joinpoint回归模型分析2004—2020年我国居民COPD死亡率变化趋势。 结果： 2004—2020年我国居民COPD死亡率（AAPC=-3.68%，P<0.001），年龄调整死亡率（AAPC=-7.27%，P<0.001）均呈下降趋势；城市居民和农村居民COPD死亡率均呈下降趋势（AAPC=-3.62%，P=0.009；AAPC=-3.23%，P=0.014），年龄调整死亡率也均呈下降趋势（AAPC=-7.26%，P<0.001；AAPC=-6.78%，P<0.001），且农村居民总体高于城市居民（P<0.001）；男性和女性COPD死亡率均呈下降趋势（AAPC=-3.00%，P<0.001；AAPC=-4.37%，P<0.001），年龄调整死亡率也均呈下降趋势（AAPC=-6.73%，P<0.001；AAPC=-8.11%，P<0.001），且男性总体高于女性（P<0.001）；地区维度，2004—2020年我国东部、中部和西部地区居民COPD死亡率均呈下降趋势（AAPC=-3.87%，P<0.001；AAPC=-3.12%，P<0.001；AAPC=-1.37%，P=0.001），其中，西部地区COPD死亡率明显高于中部地区（P<0.001）和东部地区（P<0.001）；年龄维度，2004—2020年我国居民<45、45~59、≥60岁年龄组COPD死亡率均呈下降趋势（AAPC=-9.48%，P<0.001；AAPC=-9.03%，P<0.001；AAPC=-5.91%，P<0.001），其中，≥60岁年龄组COPD死亡率明显高于<45（P<0.001）和45~59（P<0.001）岁年龄组，且下降速度最为缓慢。 结论： 2004—2020年我国居民COPD死亡率整体呈下降趋势，西部地区、农村居民、男性以及老年群体是COPD健康干预重点人群。.