Copper-catalyzed asymmetric propargylation of imines enabled by a biphenol-based phosphoramidite ligand
磷酰胺
化学
催化作用
配体(生物化学)
组合化学
铜
有机化学
受体
生物化学
寡核苷酸
DNA
作者
Qiqi Yan,Cheng-Kai Ruan,Yu-Qin Deng,Yu-Chuan Pu,Wen‐Dao Chu,Cheng‐Yu He,Quan‐Zhong Liu
出处
期刊:Organic chemistry frontiers [The Royal Society of Chemistry] 日期:2023-01-01卷期号:10 (19): 4935-4940被引量:1
标识
DOI:10.1039/d3qo00871a
摘要
Cu-catalyzed asymmetric propargylation of acyclic imines with electron-neutral protecting groups was established, providing the corresponding homopropargyl amines in excellent yields and high enantioselectivities.